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Computational Protocol for Screening GPI-anchored Proteins - SpringerLink
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We have developed a novel computational protocol for identifying GPI-anchored proteins, which is more accurate than previously proposed protocols. It uses an ...
Abstract. Glycosylphosphatidylinositol (GPI) lipid modification is an important protein posttranslational modification found in many organ-.
Computational methods were developed to discriminate proteins that undergo this post-translational modification starting from their aminoacidic sequences.
NetGPI is based on recurrent neural networks, incorporating an attention mechanism that simultaneously detects GPI-anchoring signals and points out the location ...
Missing: Protocol Screening
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Sep 12, 2019 · In this study, we characterized the B. malayi GPI-anchored proteome using both computational and experimental approaches. We used bioinformatic ...
Missing: Screening | Show results with:Screening
A Kohonen self-organizing map, GPI-SOM, was developed that predicts GPI-anchored proteins with high accuracy.
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Oct 12, 2020 · GPI-anchored proteins have two signals in their primary sequence: an N-terminal sequence for endoplasmic retic- ulum targeting (signal peptide) ...
Jan 25, 2023 · FT-GPI-based prediction is a useful tool for mining GPI-APs and gaining further insights into their evolution and sequence diversity.
May 11, 2020 · In the present work, we devise a coarse-grained model of a full GPI and GPI-anchored green fluorescent protein (GFP) based on the MARTINI force ...
Jan 7, 2021 · GPI-anchors constitute a very important post-translational modification, linking many proteins to the outer face of the plasma membrane in ...